Osteoarthritis Patient Registry
What is a Patient Registry Study?
A patient registry study is set up to collect information about how well treatments for medical conditions, work in real-world.
Unlike clinical trials, registries do not assign patients to specific treatments. Instead, patients and their physicians choose the treatment that best fits their needs, and outcomes are tracked over time.
Innovations in Genicular Outcomes (IGOR)
A first-of-its-kind registry for OA knee pain interventions
Progress in the management of osteoarthritis of the knee remains limited due to critical gaps in our scientific understanding and therapeutic capabilities.
Traditional randomized controlled trials (RCTs) often exclude patients with comorbidities, those at the extremes of age or BMI, or those receiving other pain treatments, limiting generalizability of findings. In addition, many studies fail to incorporate patient-reported outcomes (PROs) that reflect the lived experience of OA, such as functional limitations, sleep disturbances, and quality of life. Greater integration of real-world data with long-term data capture and PROs is necessary to inform patient centered care and to align research priorities with clinical relevance.
For over a decade, Pacira BioSciences Inc. has led the way in targeted, non-opioid pain management. We continue to build on that legacy by driving innovation and lasting change in managing musculoskeletal pain and adjacencies with opioid-sparing strategies
About IGOR
IGOR is a multi-center, multi-treatment, multi-outcome long-term registry that has the potential to provide valuable insights into safety, clinical effectiveness, patient response and economic outcomes of various treatment methods over time in real world practice, including oral medications, intra-articular injections, and non-drug treatments such as cryoneurolysis through knee replacement surgery.
These insights can provide valuable information to help guide best practices for current surgical and non-surgical treatments of knee osteoarthritis, as well as inform the development of future therapies by providing a better understanding of patient characteristics and treatment response.
Recognizing that osteoarthritis pain management spans multiple treatment paradigms, the IGOR registry was designed and is being conducted in collaboration with a multi-disciplinary team of specialists in orthopedic surgery, sports medicine, physiatry, rheumatology, and family medicine.
The robust design of IGOR is intended to capture real-world data across a broad range of osteoarthritis treatments, reflecting each patient’s dynamic care journey over an extended period.
The study collects robust patient characteristics, as well as clinical, economic and patient-reported outcomes, with patients contributing data over several years across multiple interventions.
Much of this outcomes data is gathered directly from enrolled patients and clinical settings, with long-term engagement contributing to high quality, meaningful insights.
Real-World Evidence
With over 3000 patients enrolled over several years, this robust knee osteoarthritis database is yielding high-quality real-world evidence and generating valuable insights into a range of interventions.
These insights have the potential to significantly influence how knee pain is treated, ultimately improving patient outcomes. Key areas of focus include pain, functional outcomes, opioid utilization, and quality-of-life assessments.
Access Key Resources for HCPs
OA Patient Registry Protocol
Review the full study details on
ClinicalTrials.gov
OA Patient Registry Infographic
Download this infographic to learn more about the IGOR registry